2019
- Marchi S, Vitto VAM, Danese A, Wieckowski MR, Giorgi C and Pinton P "Mitochondrial calcium uniporter complex modulation in cancerogenesis" Cell Cycle - in press
- Malińska D., Więckowski MR., Michalska B., Drabik K., Prill M., Patalas-Krawczyk P., Walczak J., Szymański J., Mathis C., Van der Toorn M., Luettich K., Hoeng J., Peitsch MC., Duszyński J. and Szczepanowska J. "Mitochondria as a possible target for nicotine action" Journal of Bioenergetics and Biomembranes - in press
- Tarocco A, Caroccia N, Morciano G, Wieckowski MR, Ancora G, Garani G, Pinton P "Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care" Cell Death Disease - in press
- Gonçalo C. Pereira, Susana P. Pereira, José A. Lumini, Claudia V. Pereira, James A. Bjork, José Magalhães, António Ascensão, Maria S. Santos, António J. Moreno, Mariusz R. Więckowski, Kendall B. Wallace and Paulo J. Oliveira “Early Cardiac Mitochondrial Molecular and Functional Responses to Acute Anthracycline Treatment in Wistar Rats” Toxicological Sciences - in press
- Flis D.J., Dzik K., Kaczor J.J., Cieminski K., Halon-Golabek M., Antosiewicz J., Wieckowski M.R. and Ziolkowski W. “Swim training modulates mouse skeletal muscle energy metabolism and ameliorates reduction in grip strength at the early stage of Amyotrophic Lateral Sclerosis disease” International Journal of Molecular Sciences, 2019 Jan 9;20(2). pii: E233. doi: 10.3390/ijms20020233
- Walczak J, Dębska-Vielhaber G, Vielhaber S, Szymański J, Charzyńska A, Duszyński J, Szczepanowska J. "Distinction of sporadic and familial forms of ALS based on mitochondrial characteristics" FASEB J. 2018 Dec 14:fj201801843R. doi: 10.1096/fj.201801843R.
- Bonora M, Wieckowski MR, Sinclair DA, Kroemer G, Pinton P, Galluzzi L (2018) "Targeting mitochondria for cardiovascular disorders: therapeutic potential and persisting obstacles" Nature Reviews Cardiology 2019 Jan;16(1):33-55.
2018
- Grattagliano I, Montezinho LP, Oliveira PJ, Frühbeck G, Gómez-Ambrosi J, Montecucco F, Carbone F, Wieckowski MR, Wang DQ, Portincasa P. "Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease" Biochem Pharmacol. 2018 Nov 30;160:34-45.
- Paulina Jędrak, Paweł Mozolewski, Grzegorz Węgrzyn and Mariusz R. Więckowski (2018) "Mitochondrial alterations accompanied by oxidative stress conditions in skin fibroblasts of Huntington's disease patients" Metabolic Brain Disease - 2018 Dec;33(6):2005-2017
- Morciano G, Preti D, Pedriali G, Aquila G, Missiroli S, Fantinati A, Caroccia N, Pacifico S, Bonora M, Talarico A, Morganti C, Rizzo P, Ferrari R, Wieckowski MR, Campo G, Giorgi C, Trapella C, Pinton P. (2018) Discovery of novel 1,3,8-triazaspiro[4.5]decane derivatives that target the c subunit of F1/FO-adenosine triphosphate (ATP) synthase for the treatment of reperfusion damage in myocardial infarction. Journal of Medicinal Chemistry - 2018 Aug 23;61(16):7131-7143.
- Claudia Morganti, Sonia Missiroli, Magdalena Lebiedzinska-Arciszewska, Letizia Ferroni, Lucia Morganti, Mariasole Perrone, Daniela Ramaccini, Savino Occhionorelli, Barbara Zavan, Mariusz R. Wieckowski and Carlotta Giorgi (2018) Regulation of PKCβ levels and autophagy by PML is essential for high glucose-dependent mesenchymal stem cells adipogenesis. International Journal of Obesity - 2018 Aug 6. doi: 10.1038/s41366-018-0167-1
- Gregorczyk KP, Wyżewski Z, Szczepanowska J, Toka FN, Mielcarska MB, Bossowska-Nowicka M, Gieryńska M, Boratyńska-Jasińska A, Struzik J, Niemiałtowski MG, Szulc-Dąbrowska L. Ectromelia Virus Affects Mitochondrial Network Morphology, Distribution, and Physiology in Murine Fibroblasts and Macrophage Cell Line. Viruses. 2018 May 16;10(5).
- Wyżewski Z, Gregorczyk KP, Szczepanowska J, Szulc-Dąbrowska L. Functional role of Hsp60 as a positive regulator of human viral infection progression. Acta Virol. 2018;62(1):33-40.
- Michalska BM, Kwapiszewska K, Szczepanowska J, Kalwarczyk T, Patalas-Krawczyk P, Szczepański K, Hołyst R, Duszyński J and Szymański J. Insight into the fission mechanism by quantitative characterization of Drp1 protein distribution in the living cell. Sci Rep. 2018 May 25;8(1):8122.
- Claudia Morganti, Massimo Bonora, Luigi Sbano, Giampaolo Morciano, Giorgio Aquila, Gianluca Campo, Mariusz R. Wieckowski, Carlotta Giorgi, Paolo Pinton "The mitochondrial permeability transition pore" Mitochondrial Biology and Experimental Therapeutics - 2018, Pages 47-73
- Carlotta Giorgi*, Saverio Marchi*, Ines C.M. Simoes*, Ziyu Ren*, Giampaolo Morciano*, Mariasole Perrone, Paulina Patalas-Krawczyk, Sabine Borchard, Paulina Jędrak, Karolina Pierzynowska, Jędrzej Szymański, David Q. Wang, Piero Portincasa, Grzegorz Węgrzyn, Hans Zischka, Pawel Dobrzyn, Massimo Bonora, Jerzy Duszynski, Alessandro Rimessi, Agnieszka Karkucinska-Wieckowska, Agnieszka Dobrzyn, Gyorgy Szabadkai, Barbara Zavan, Paulo J. Oliveira, Vilma A. Sardao, Paolo Pinton and Mariusz R. Wieckowski (2018) "MITOCHONDRIA AND REACTIVE OXYGEN SPECIES IN AGING AND AGE-RELATED DISEASES" International Review of Cell and Molecular Biology - 2018;340:209-344.
- Giampaolo Morciano, Saverio Marchi, Claudia Morganti, Luigi Sbano, Mart Bittremieux, Martijn Kerkhofs, Mariangela Corricelli, Alberto Danese, Agnieszka Karkucinska-Wieckowska, Mariusz R. Wieckowski, Geert Bultynck, Carlotta Giorgi, Paolo Pinton (2018) “Mitochondria-associated ER membranes (MAMs) in cancer-specific environmental settings” Neoplasia 2018 May;20(5):510-523.
- Damian Flis, Katarzyna Dzik, Jan Kaczor, Malgorzata Halon-Golabek, Jedrzej Antosiewicz, Mariusz R. Wieckowski and Wieslaw Ziolkowski (2018) "Swim training modulates skeletal muscle energy metabolism, oxidative stress and the mitochondrial cholesterol content in Amyotrophic Lateral Sclerosis mice " Oxidative Medicine and Cellular Longevity - 2018 Apr 11;2018:5940748.
- Konarzewski M, Zabielski R, Kowalczyk R and Duszyński J. "Białowieża Forest: Logging data lacking." Science. 2018 Feb 9;359(6376):646.
- Dominika Malińska, Jędrzej Szymański, Paulina Patalas-Krawczyk, Bernadeta Michalska, Aleksandra Wojtala, Monika Prill, Małgorzata Partyka, Karolina Drabik, Jarosław Walczak, Alain Sewer, Stephanie Johne, Karsta Luettich, Manuel C Peitsch, Julia Hoeng, Jerzy Duszyński, Joanna Szczepanowska*, Marco van der Toorn* and Mariusz R. Wieckowski* "Assessment of Mitochondrial Function Following Short- and Long-term Exposure of Human Bronchial Epithelial Cells to Total Particulate Matter from a Candidate Modified-risk Tobacco Product and Reference Cigarettes" Food and Chemical Toxicology, 2018 May;115:1-12
- Inês C.M. Simões, Adriana Fontes, Paolo Pinton, Hans Zischka and Mariusz R. Wieckowski, "Mitochondria in non-alcoholic fatty liver disease" The International Journal of Biochemistry & Cell Biology 2018 Feb; 95:93–99
- Justyna Janikiewicz*, Jędrzej Szymański*, Dominika Malinska, Paulina Patalas- Krawczyk, Bernadeta Michalska, Jerzy Duszyński, Carlotta Giorgi, Massimo Bonora, Agnieszka Dobrzyn and Mariusz R. Wieckowski# (2018) "Mitochondria-associated membranes in aging and senescence: structure, function and dynamics" Cell Death & Disease - 2018 Feb 28;9(3):332.
- Sonia Missiroli, Simone Patergnani, Natascia Caroccia, Gaia Pedriali, Mariasole Perrone, Maurizio Previati, Mariusz R. Wieckowski and Carlotta Giorgi (2018) "Mitochondria Associated Membranes (MAMs) and inflammation" Cell Death & Disease - 2018 Feb 28;9(3):329.
- Mariusz R. Wieckowski, Alberto Danese, Giampaolo Morciano, Maciej Pronicki, Jerzy Duszynski, Paolo Pinton and Agnieszka Karkucinska-Wieckowska "Recovering mitochondrial function in patients’ fibroblasts" Mitochondrial Biology and Experimental Therapeutics - 2018, pp 359-378
- Marchi S, Patergnani S, Missiroli S, Morciano G, Rimessi A, Wieckowski MR, Giorgi C, Pinton P. “Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death.” Cell Calcium, Cell Calcium. 2018 Jan;69:62-72
2017
- Walczak J, Partyka M, Duszyński J, Szczepanowska J (2017) "Implications of mitochondrial network organization in mitochondrial stress signalling in NARP cybrid and Rho0 cells” Sci. Rep. Nov 1;7(1):14864.
- Kalwarczyk T, Kwapiszewska K, Szczepanski K, Sozanski K, Szymanski J, Michalska B, Patalas-Krawczyk P, Duszynski J, Holyst R. (2017) “Apparent Anomalous Diffusion in the Cytoplasm of Human Cells: The Effect of Probes' Polydispersity” J Phys Chem B. Oct 26;121(42):9831-9837.
- Pedriali G, Rimessi A, Sbano L, Giorgi C, Wieckowski MR, Previati M and Pinton P. "Regulation of ER-mitochondria Ca2+ transfer and its importance for anti-cancer therapies" Frontiers in Oncology, section Molecular and Cellular Oncology, 2017, Aug 31;7:180.
- Jędrzej Szymański, Justyna Janikiewicz, Bernadeta Michalska, Paulina Patalas-Krawczyk, Mariasole Perrone, Wiesław Ziółkowski, Jerzy Duszynski, Paolo Pinton, Agnieszka Dobrzyń and Mariusz R. Wieckowski (2017) "Interaction of mitochondria with the endoplasmic reticulum and plasma membrane in calcium homeostasis, lipid trafficking and mitochondrial structure" International Journal of Molecular Sciences, Jul 20;18(7). pii: E1576. doi: 10.3390/ijms18071576.
- Aleksandra Wojtala, Agnieszka Karkucinska-Wieckowska, Vilma A Sardao, Joanna Szczepanowska, Pawel Kowalski, Maciej Pronicki, Jerzy Duszynski and Mariusz R. Wieckowski (2017) "Modulation of mitochondrial dysfunction-related oxidative stress in fibroblasts of patients with Leigh syndrome by inhibition of prooxidative p66Shc pathway" Mitochondrion, 2017 Jul 21. pii: S1567-7249(16)30252-5. doi: 10.1016/j.mito.2017.07.002.
- Antosiewicz A, Jarmuła A, Przybylska D, Mosieniak G, Szczepanowska J, Kowalkowska A, Rode W and Cieśla J. "Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells." J Biomol Struct Dyn. 2017 May;35(7):1474-1490
- Massimo Bonora, Claudia Morganti, Giampaolo Morciano, Gaia Pedriali, Magdalena Lebiedzinska-Arciszewska, Giorgio Aquila, Carlotta Giorgi, Paola Rizzo, Gianluca Campo, Roberto Ferrari, Guido Kroemer, Mariusz R. Wieckowski#, Lorenzo Galluzzi#, and Paolo Pinton# "Mitochondrial permeability transition involves dissociation of F1FO ATP synthase dimers and C-ring conformation" EMBO Reports; 2017 Jul;18(7):1077-1089. doi: 10.15252/embr.201643602.
- Morciano G, Bonora M, Campo G, Aquila G, Rizzo P, Giorgi C, Wieckowski MR, Pinton P "Mechanistic Role of mPTP in Ischemia-Reperfusion Injury" Adv. Exp. Med. Biol.; 2017; 982:169-189. doi: 10.1007/978-3-319-55330-6_9.
- José Teixeira, Daniel Chavarria, Fernanda Borges, Lech Wojtczak, Mariusz R. Wieckowski, Agnieszka Karkucińska-Wieckowska* and Paulo J. Oliveira* "Dietary Polyphenols and Mitochondrial Function: Role in Health and Disease" (2017) Current Medicinal Chemistry; in press doi: 10.2174/0929867324666170529101810.
- Catia V. Diogo, Claudia M. Deus, Magdalena Liebiedzinska-Arciszewska, Aleksandra Wojtala, Mariusz R. Wieckowski and Paulo J. Oliveira “Carvedilol and antioxidant proteins in a type I diabetes animal model” European Journal of Clinical Investigation; 2017 Jan;47(1):19-29.
- Dolores Del Prete, Jan M. Suski, Bénédicte Oulès, Delphine Debayle, Anne Sophie Gay, Sandra Lavas-Gervais, Renaud Bussiere, Charlotte Bauer, Paolo Pinton, Patrizia Paterlini-Bréchot, Mariusz R. Wieckowski, Frédéric Checler and Mounia Chami "Localization and processing of the β-amyloid precursor protein in Mitochondria-associated membranes" Journal of Alzheimer's Disease; 2017;55(4):1549-1570
- Danese A, Patergnani S, Bonora M, Wieckowski MR, Previati M, Giorgi C, Pinton P. Calcium regulates cell death in cancer: roles of the mitochondria and mitochondria-associated membranes (MAMs). Biochim Biophys Acta. 2017 Jan 10. pii: S0005-2728(17)30004-X. doi: 10.1016/j.bbabio.2017.01.003.
- Patergnani S, Fossati V, Bonora M, Giorgi C, Marchi S, Missiroli S, Rusielewicz T, Wieckowski MR, Pinton P. Mitochondria in Multiple Sclerosis: Molecular Mechanisms of Pathogenesis. Int Rev Cell Mol Biol. 2017;328:49-103. doi: 10.1016/bs.ircmb.2016.08.003.
2016
- Peter Schönfeld and Lech Wojtczak "Short- and medium-chain fatty acids in energy metabolism: the cellular perspective" J. Lipid Res. 2016; 57, 943-954.
- Woś M, Szczepanowska J, Pikuła S, Tylki-Szymańska A, Zabłocki K, Bandorowicz-Pikuła J. “Mitochondrial dysfunction in fibroblasts derived from patients with Niemann-Pick type C disease.” Arch Biochem Biophys. 2016 Mar 1;593:50-9.
- Szulc-Dabrowska L, Gregorczyk KP, Struzik J, Boratynska-Jasinska A, Szczepanowska J, Wyzewski Z, Toka FN, Gierynska M, Ostrowska A, Niemialtowski MG. “Remodeling of the fibroblast cytoskeletal architecture during the replication cycle of Ectromelia virus: A morphological in vitro study in a murine cell line.” Cytoskeleton (Hoboken). 2016 Aug;73(8):396-417.
- Antosiewicz A, Jarmuła A, Przybylska D, Mosieniak G, Szczepanowska J, Kowalkowska A, Rode W, Cieśla J. “Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells.” J Biomol Struct Dyn. 2016 Aug 5:1-17.
- Lech Wojtczak and Mariusz R. Więckowski (2016) "From mitochondrial large amplitude swelling to the permeability transition – a short historic overview." Postępy Biochemii - Tom 62, Nr 2, p: 298 - 302
- Karolina Drabik, Dominika Malińska, Jerzy Duszyński and Joanna Szczepanowska "Mechanisms of mitochondrial transport and distribution within the cell” Postępy Biochemii, 2016; Tom 62, Nr 2, p: 182-188
- Małgorzata Partyka, Jerzy Duszyński and Joanna Szczepanowska “Changes of mitochondrial dynamics as a response to mitochondrial stress in models of sporadic Parkinson’s disease” Postępy Biochemii, 2016; Tom 62, Nr 2, p: 173-181
- Bernadeta Michalska, Jerzy Duszyński and Jędrzej Szymański “Mechanism of mitochondrial fission – structure and function of Drp1 protein” Postępy Biochemii, 2016; Tom 62, Nr 2, p: 127-137
- Alessandro Rimessi, Maurizio Previati, Federica Nigro, Mariusz R. Wieckowski♯ and Paolo Pinton♯ "Mitochondrial Reactive Oxigen Species and inflammation: molecular mechanisms, diseases and promising therapies." The International Journal of Biochemistry and Cell Biology - 2016 Dec;81(Pt B):281-293
- Monika Oparka*, Jarosław Walczak*, Dominika Malinska*, Lisanne M.P.E. van Oppen*, Joanna Szczepanowska, Werner J.H. Koopman and Mariusz R. Wieckowski "Quantifying ROS levels using CM-H2DCFDA and HyPer” Methods 2016 Jun 11. pii: S1046-2023(16)30172-4
- Massimo Bonora, Claudia Morganti, Giampaolo Morciano, Carlotta Giorgi, Mariusz R. Wieckowski and Paolo Pinton "Comprehensive analysis of mitochondrial permeability transition pore activities in living cells using imaging techniques" Nature Protocols, 2016 Jun;11(6):1067-1080.
- Carlotta Giorgi, Massimo Bonora, Sonia Missiroli, Claudia Morganti, Giampaolo Morciano, Mariusz R. Wieckowski and Paolo Pinton (2016) Alterations in mitochondrial and endoplasmic reticulum signaling by p53 mutants. Front. Oncol. - Molecular and Cellular Oncology - 2016 Feb 25;6:42
- Susana F. Sampaio, Ana F. Branco, Aleksandra Wojtala, Ignacio Vega-Naredo, Mariusz R. Wieckowski and Paulo J. Oliveira (2016) p66Shc Signaling is Involved in Stress Responses Elicited by Anthracycline Treatment of Rat Cardiomyoblasts. Archives of Toxicology 2016 Jul;90(7):1669-84.
2015
- Kalwarczyk T, Sozanski K, Ochab-Marcinek A, Szymanski J, Tabaka M, Hou S, Holyst R. (2015) Motion of nanoprobes in complex liquids within the framework of the length-scale dependent viscosity model. Adv Colloid Interface Sci, 223 : 55-63
- Massimo Bonora, Mariusz R. Wieckowski, Christos Chinopoulos, Oliver Kepp, Guido Kroemer, Lorenzo Galluzzi and Paolo Pinton (2015) "Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition" Oncogene - 34(12) : 1475-1486
- Mariusz R. Wieckowski, Claudia M. Deus, Renata Couto, Monika Oparka, Magdalena Lebiedzinska-Arciszewska, Jerzy Duszynski and Paulo J. Oliveira (2015) Measuring p66Shc Signaling Pathway Activation and Mitochondrial Translocation in Cultured Cells Curr. Protoc. Toxicol. – 2015 Nov 2;66:25.6.1-25.6.21
- Rimessi A, Patergnani S, Bonora M, Wieckowski MR, Pinton P. (2015) Mitochondrial Ca(2+) Remodeling is a Prime Factor in Oncogenic Behavior. Front Oncol. - 2015 Jun 25;5:143.
- Wojewoda M, Walczak J, Duszyński J and Szczepanowska J. "Selenite activates the ATM kinase-dependent DNA repair pathway in human osteosarcoma cells with mitochondrial dysfunction." Biochem Pharmacol. 2015 - Jun 1;95(3):170-6
- Carlotta Giorgi, Massimo Bonora , Giovanni Sorrentino, Sonia Missiroli, Federica Poletti, Jan M Suski, Fabian Galindo Ramirez, Rosario Rizzuto, Francesco Di Virgilio, Ester Zito, Pier Paolo Pandolfi, Mariusz R Wieckowski, Fabio Mammano, Giannino Del Sal, Paolo Pinton (2015) "P53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner" Proceedings of the National Academy of Sciences (PNAS) - Feb 10;112(6):1779-84.
- Carlotta Giorgi, Sonia Missiroli, Simone Patergnani, Mariusz R Wieckowski and Pinton P. (2015) Mitochondria-Associated Membranes (MAMs): Composition, Molecular Mechanisms and Physiopathological Implications. Antioxidants & Redox Signaling - Apr 20;22(12):995-1019.
- Felix Distelmaier, Federica Valsecchi, Dania C. Liemburg-Apers, Magdalena Lebiedzinska, Richard J. Rodenburg, Sandra Heil, Jaap Keijer, Jack Fransen, Hiromi Imamura, Katharina Danhauser, Benoit Viollet, Frank N. Gellerich, Jan A.M. Smeitink, Mariusz R. Wieckowski, Peter H.G.M. Willems and Werner J.H. Koopman (2015) Mitochondrial dysfunction triggers an adaptive cell survival program that requires AMPK-α BBA - Molecular Basis of Disease – 1852(3):529-40.
- Giampaolo Morciano, Carlotta Giorgi, Massimo Bonora, Silvia Punzetti, Rita Pavasini, Mariusz R. Wieckowski, Gianluca Campo and Paolo Pinton (2014) "Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury" Journal of Molecular and Cellular Cardiology 2015; 78:142-153
- Magdalena Lebiedzinska-Arciszewska*, Monika Oparka*, Ignacio Vega Naredo, Agnieszka Karkucinska-Wieckowska, Paolo Pinton, Jerzy Duszynski and Mariusz R. Wieckowski "The interplay between p66Shc, Reactive Oxygen Species and cancer cell metabolism" European Journal of Clinical Investigation 2015; 1:25-31
- Agnieszka Karkucinska-Wieckowska, Maciej Pronicki and Mariusz R. Wieckowski "Histoenzymatic methods for visualization of the activity of individual mitochondrial respiratory chain complexes in the muscle biopsies from patients with mitochondrial defects" Methods Molecular Biology 2015; 1241:85-93
- Mariusz R. Wieckowski and Lech Wojtczak "Isolation of crud mitochondrial fraction from cells" Methods Molecular Biology - 2015;1241:1-8
2014
- Lech Wojtczak "Półwiecze „chemiosmotycznej” koncepcji sprzężenia energetycznego" Postępy Bioch. 2014; 60, 33-38.
- Marcin Tabaka, Tomasz Kalwarczyk, Jedrzej Szymanski, Sen Hou and Robert Holyst (2014) The effect of macromolecular crowding on mobility of biomolecules, association kinetics, and gene expression in living cells Front. Phys. - in press
- Alster O, Bielak-Zmijewska A, Mosieniak G, Moreno-Villanueva M, Dudka-Ruszkowska W, Wojtala A, Kusio-Kobiałka M, Korwek Z, Burkle A, Piwocka K, Siwicki JK, Sikora E. "The role of nibrin in doxorubicin-induced apoptosis and cell senescence in Nijmegen Breakage Syndrome patients lymphocytes." PLoS One - 2014; Volume 9; Issue 8; e104964
- Wyżewski Z, Gregorczyk KP, Szulc-Dąbrowska L, Struzik J, Szczepanowska J, Niemiałtowski M. Cooperation between heat shock proteins in organizing of proteins spatial structure. Postepy Hig Med Dosw. 2014 Jun 9;68(0):793-807
- Marchi S, Giorgi C, Oparka M, Duszynski J, Wieckowski MR, Pinton P (2014) "Oncogenic and oncosuppressive signal transduction at mitochondria-associated endoplasmic reticulum membranes (MAM)" Molecular & Cellular Oncology - 2014; Volume 1, Issue 2; e956469 1-10
- Annalisa Camporeale, Marco Demaria, Emanuele Monteleone, Carlotta Giorgi, Mariusz R. Wieckowski, Paolo Pinton, Valeria Poli (2014) "STAT3 activities and energy metabolism: dangerous liaisons" Cancers - 2014 Jul 31;6(3):1579-96
- Dymkowska D, Drabarek B, Podszywałow-Bartnicka P, Szczepanowska J, Zabłocki K. Hyperglycaemia modifies energy metabolism and reactive oxygen species formation in endothelial cells in vitro. Arch Biochem Biophys. 2014 Jan 15;542:7-13
- Marleen Forkink; Ganesh R Manjeri; Dania C Liemburg-Apers; Esther Nibbeling; Maxime Blanchard; Aleksandra Wojtala; Jan Smeitink; Mariusz R. Wieckowski; Peter Willems and Werner J.H. Koopman "Mitochondrial hyperpolarization during chronic complex I inhibition is sustained by low activity of complex II, III, IV and V" Biochimica et Biophysica Acta - Bioenergetics 2014 Aug;1837(8):1247-56.
- Massimo Bonora*, Elena De Marchi*, Simone Patergnani*, Jan M. Suski*, Fulvio Celsi, Angela Bononi, Carlotta Giorgi, Saverio Marchi, Alessandro Rimessi, Jerzy Duszyński, Tullio Pozzan, Mariusz R. Wieckowski# and Paolo Pinton# "Tumor necrosis factor-α impairs oligodendroglial differentiation through a mitochondria-dependent process" Cell Death and Differentiation 2014 Aug;21(8):1198-208
- Aleksandra Wojtala*, Massimo Bonora*, Dominika Malinska*, Paolo Pinton, Jerzy Duszynski and Mariusz R. Wieckowski "Methods to monitor mitochondrial and cellular ROS production by fluorescence microscopy and fluorometry" Methods in Enzymology (Oncometabolism) 2014;542:243-62
- Simone Patergnani, Federica Baldassari, Elena De Marchi, Agnieszka Karkucinska-Wieckowska, Mariusz R. Wieckowski and Paolo Pinton "Methods to monitor mitochondrial versus glycolytic ATP production in cellula" Methods in Enzymology (Oncometabolism) 2014;542:313-32
- Jan M. Suski, Magdalena Lebiedzinska, Aleksandra Wojtala, Jerzy Duszynski, Carlotta Giorgi, Paolo Pinton and Mariusz R. Wieckowski (2014) "Isolation of plasma membrane-associated membranes from rat liver" Nature Protocols Feb;9(2):312-22
- Dorota Piekutowska-Abamczuk, Maciej Pronicki, Katarzyna Strawa, Tamara Szymańska-Dębińska, Agnieszka Karkucińska-Więckowska, Anna Fidziańska, Mariusz R. Więckowski, Dorota Jurkiewicz, Elżbieta Ciara, Irena Jankowska, Jolanta Sykut-Cegielska, Rafał Płoski, Ewa Pronicka "Novel c.191C>G (p.Pro64Arg) MPV17 gene mutation identified in two pairs of unrelated Polish siblings with mitochondrial hepatoencephalopathy" Clinical Genetics 2014 Jun;85(6):573-7
2013
- Schönfeld P, Siemen D, Kreutzmann P, Franz C, Wojtczak L. (2013) Interaction of the antibiotic minocycline with liver mitochondria - role of membrane permeabilization in the impairment of respiration. FEBS J. 2013; 280(24):6589-99
- Karkucinska-Wieckowska A, Trubicka J, Werner B, Kokoszynska K, Pajdowska M, Pronicki M, Czarnowska E, Lebiedzinska M, Sykut-Cegielska J, Ziolkowska L, Jaron W, Dobrzanska A, Ciara E, Wieckowski MR, Pronicka E. (2013) Left ventricular noncompaction (LVNC) and low mitochondrial membrane potential are specific for Barth syndrome. J Inherit Metab Dis. Nov;36(6):929-37.
- Ana F. Branco, Susana Sampaio, Mariusz R. Wieckowski, Vilma Sardão, Paulo J. Oliveira (2013) "Mitochondrial Disruption Occurs Downstream from β-adrenergic Overactivation by Isoproterenol in Differentiated, but not Undifferentiated H9c2 Cardiomyoblasts: Differential Activation of Stress and Survival Pathways" International Journal of Biochemistry & Cell Biology 45(11):2379-91
- Piotr Bednarczyk, Mariusz R. Wieckowski, Malgorzata Broszkiewicz, Krzysztof Skowronek, Detlef Siemen and Adam Szewczyk (2013) "Putative structural and functional coupling of the mitochondrial BKCa channel to the respiratory chain" Plos One 8(6):e68125
- Yao Z, Jones AW, Fassone E, Sweeney MG, Lebiedzinska M, Suski JM, Wieckowski MR, Tajeddine N, Hargreaves IP, Yasukawa T, Tufo G, Brenner C, Kroemer G, Rahman S, Szabadkai G (2013) PGC-1β Mediates Adaptive Chemoresistance Associated with Mitochondrial DNA Mutations. Oncogene 32(20):2592-600
- Elena De Marchi, Federica Baldassari, Angela Bononi, Mariusz R. Wieckowski and Paolo Pinton (2013) Oxidative stress in cardiovascular diseases and obesity : role of p66Shc and protein kinase C. Oxidative Medicine and Cellular Longevity 2013:564961
- Maciej Pronicki, Tamara Szymańska-Dębińska, Agnieszka Karkucińska-Więckowska and Mariusz Roman Więckowski (2013) Autopsy in a child with suspicion of mitochondrial disease. Standardy Medyczne Pediatra 10(1):90-94
- Bonora M, Bononi A, De Marchi E, Giorgi C, Lebiedzinska M, Marchi S, Patergnani S, Rimessi A, Suski JM, Wojtala A, Wieckowski MR, Kroemer G, Galluzzi L, Pinton P. (2013) Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition. Cell Cycle 12(4):674-83
- Lebiedzinska M, Karkucinska-Wieckowska A, Wojtala A, Suski JM, Szabadkai G, Wilczynski G, Wlodarczyk J, Diogo CV, Oliveira PJ, Tauber J, Ježek P, Pronicki M, Duszynski J, Pinton P, Wieckowski MR. (2013) Disrupted ATP synthase activity and mitochondrial hyperpolarisation-dependent oxidative stress is associated with p66Shc phosphorylation in fibroblasts of NARP patients. International Journal of Biochemistry and Cell Biology 45(1):141-50
- Janska H, Kwasniak M, Szczepanowska J. (2013) Protein quality control in organelles - AAA/FtsH story. Biochim Biophys Acta – Mol. Cell Res 1833(2):381-7
- Diogo CV, Suski JM, Lebiedzinska M, Wojtala A, Duszynski J, Karkucinska-Wieckowska A, Pronicki M, Pinton P, Portincasa P, Oliveira PJ, Wieckowski MR. (2013) Cardiac mitochondrial dysfunction during hyperglycaemia: the role of oxidative stress and p66Shc signalling. International Journal of Biochemistry and Cell Biology 45(1):114-22
2012
- Suski JM, Shönfeld P, Bonora M, Shabalina I, Pinton P, Wieckowski MR. (2012) Guanosine diphosphate exerts a lower effect on superoxide release from mitochondrial matrix in the brains of uncoupling protein-2 knockout mice: New evidence for a putative novel function of uncoupling proteins as superoxide anion transporters. Biochemical and Biophysical Research Communications, 428 (12):234-238
- Schönfeld P, Wojtczak L. (2012) Brown adipose tissue mitochondria oxidizing fatty acids generate high levels of reactive oxygen species irrespective of the uncoupling protein-1 activity state. Biochimica et Biophysica Acta – Bioenergetics 1817, 410-418
- Szczepanowska J, Malinska D, Wieckowski MR, Duszynski J. (2012) Effect of mtDNA point mutations on cellular bioenergetics. Biochimica et Biophysica Acta – Bioenergetics 1817(10):1740-6
- Bonora M, Patergnani S, Rimessi A, De Marchi E, Suski JM, Bononi A, Giorgi C, Marchi S, Missiroli S, Poletti F, Wieckowski MR, Pinton P (2012) ATP synthesis and storage. Purinergic Signalling 8(3):343-57
- Giorgi C, Agnoletto C, Bononi A, Bonora M, De Marchi E, Marchi S, Missiroli S, Patergnani S, Poletti F, Rimessi A, Suski JM, Wieckowski MR, Pinton P. (2012) Mitochondrial calcium homeostasis as potential target for mitochondrial medicine. Mitochondrion (1):77-85
- Pereira CV, Lebiedzinska M, Wieckowski MR, Oliveira PJ. (2012) Regulation and protection of mitochondrial physiology by sirtuins. Mitochondrion (1):66-76
- Wojewoda M, Duszyński J, Więckowski M, Szczepanowska J. (2012) Effect of selenite on basic mitochondrial function in human osteosarcoma cells with chronic mitochondrial stress. Mitochondrion 12(1):149-55
- Larsen AK, Malinska D, Koszela-Piotrowska I, Parhamifar L, Hunter AC, Moghimi SM. (2012) Polyethylenimine-mediated impairment of mitochondrial membrane potential, respiration and membrane integrity: implications for nucleic acid delivery and gene therapy. Mitochondrion 12(1):162-8
- Malinska D, Kudin AP, Bejtka M, Kunz WS. (2012) Changes in mitochondrial reactive oxygen species synthesis during differentiation of skeletal muscle cells. Mitochondrion 12(1):144-8
- Drabarek B, Dymkowska D, Szczepanowska J, Zabłocki K. (2012) TNFα affects energy metabolism and stimulates biogenesis of mitochondria in EA.hy926 endothelial cells. Int J Biochem Cell Biol 44(9):1390-7
- Bononi A, Missiroli S, Poletti F, Suski JM, Agnoletto C, Bonora M, De Marchi E, Giorgi C, Marchi S, Patergnani S, Rimessi A, Wieckowski MR, Pinton P (2012) Mitochondria-associated membranes (MAMs) as hotspot Ca2+ signalling units. Adv Exp Med Biol. 740:411-37
- Giorgi C, Baldassari F, Bononi A, Bonora M, De Marchi E, Marchi S, Missiroli S, Patergnani S, Rimessi A, Suski JM, Wieckowski MR, Pinton P. (2012) Mitochondrial Ca2+ and apoptosis. Cell Calcium 52(1):36-43
- Marchi S, Giorgi C, Suski JM, Agnoletto C, Bononi A, Bonora M, De Marchi E, Missiroli S, Patergnani S, Poletti F, Rimessi A, Duszynski J, Wieckowski MR, Pinton P. (2012) Mitochondria-ros crosstalk in the control of cell death and aging. J Signal Transduct. 2012:329635
- Suski JM, Lebiedzinska M, Bonora M, Pinton P, Duszynski J, Wieckowski MR. (2012) Relation between mitochondrial membrane potential and ROS formation. Methods Mol Biol. 810:183-205
2011
- Giorgi C, Wieckowski MR, Pandolfi PP and Pinton P. (2011) Mitochondria associated membranes (MAMs) as critical hubs for apoptosis. Communicative & Integrative Biology 4(3):334-5
- Patergnani S, Suski JM, Agnoletto C, Bononi A, Bonora M, De Marchi E, Giorgi C, Marchi S, Missiroli S, Poletti F, Rimessi A, Duszynski J, Wieckowski MR and Pinton P. (2011) Calcium signaling around Mitochondria Associated Membranes (MAMs). Cell Communication and Signalling 9(1):19
- Suski JM, Karkucinska-Wieckowska A, Lebiedzinska M, Giorgi C, Szczepanowska J, Szabadkai G, Duszynski J, Pronicki M, Pinton P and Wieckowski MR. (2011) p66Shc aging protein in control of fibroblasts fate. International Journal of Molecular Sciences 12(8):5373-89
- Wojtczak L, Lebiedzińska M, Suski J, Więckowski MR, Schönfeld P. (2011) Inhibition by purine nucleotides of the release of reactive oxygen species from muscle mitochondria: Indication for a function of uncoupling proteins as superoxide anion transporters. Biochem Biophys Res Commun. 407(4):772-6
- Suski J , Lebiedzinska M, Machado NG, Oliveira PJ, Pinton P, Duszynski J, Wieckowski MR. (2011) Mitochondrial tolerance to drugs and toxic agents in ageing and disease. Current Drug Targets 12(6):827-49
- Karkucinska-Wieckowska A, Lebiedzinska M, Jurkiewicz E, Pajdowska M, Trubicka J, Szymanska-Debinska T, Suski J, Pinton P, Duszynski J, Pronicki M, Wieckowski MR, Pronicka E. (2011) Increased reactive oxygen species (ROS) production and low catalase level in fibroblasts of a girl with MEGDEL association (Leigh syndrome, deafness, 3-methylglutaconic aciduria). Folia Neuropathol. 49(1):56-63
- Wojewoda M, Duszyński J, Szczepanowska J. (2011) NARP mutation and mtDNA depletion trigger mitochondrial biogenesis which can be modulated by selenite supplementation. Int J Biochem Cell Biol. 43 1178-1186
- Chmielewska L, Malińska D. (2011) Cytoprotective action of the potassium channel opener NS1619 under conditions of disrupted calcium homeostasis. Pharmacol Rep. 63:176-183
2010
- Demaria M, Giorgi C, Lebiedzinska M, Esposito G, D'Angeli L, Bartoli A, Gough DJ, Turkson J, Levy DE, Watson CJ, Wieckowski MR, Provero P, Pinton P, Poli V. (2010) A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction. Aging 2(11):823-42
- Giorgi C, Ito K, Lin HK, Santangelo C, Wieckowski MR, Lebiedzinska M, Bononi A, Bonora M, Duszynski J, Bernardi R, Rizzuto R, Tacchetti C, Pinton P, Pandolfi PP. (2010) PML Regulates Apoptosis at Endoplasmic Reticulum Modulating Calcium Release. Science 30 (6008):1247-51
- Nowis D, Maczewski M, Mackiewicz U, Kujawa M, Ratajska A, Wieckowski MR, Wilczyński GM, Malinowska M, Bil J, Salwa P, Bugajski M, Wójcik C, Siński M, Abramczyk P, Winiarska M, Dabrowska-Iwanicka A, Duszyński J, Jakóbisiak M, Golab J. (2010) Cardiotoxicity of the anticancer therapeutic agent bortezomib. Am J Pathol. 176(6):2658-68
- Ziolkowski W, Szkatula M, Nurczyk A, Wakabayashi T, Kaczor JJ, Olek RA, Knap N, Antosiewicz J, Wieckowski MR, Wozniak M. (2010) Methyl-beta-cyclodextrin induces mitochondrial cholesterol depletion and alters the mitochondrial structure and bioenergetics. FEBS Lett. 584(22):4606-10
- Schönfeld P, Wieckowski MR, Lebiedzinska M and Wojtczak L. (2010) Mitochondrial fatty acid oxidation and oxidative stress; lack of reverse electron transfer-associated production of reactive oxygen species. Biochimica et Biophysica Acta (BBA) – Bioenergetics 1797(6-7): 929-938
- Lebiedzinska M, Karkucinska-Wieckowska A, Giorgi C, Karczmarewicz E, Pronicka E, Pinton P, Duszynski J, Pronicki M and Wieckowski MR. (2010) Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders. Biochimica et Biophysica Acta (BBA) – Bioenergetics 1797(6-7): 952-960
- Malinska D, Mirandola SR, Kunz WS (2010) Mitochondrial potassium channels and reactive oxygen species. FEBS Lett. 584: 2043-2048
- Szewczyk A, Kajma A, Malinska D, Wrzosek A, Bednarczyk P, Zabłocka B, Dołowy K (2010) Pharmacology of mitochondrial potassium channels: dark side of the field. FEBS Lett. 584: 2063-2069
- Malinska D, Kulawiak B, Kudin AP, Kovacs R, Huchzermeyer C, Kann O, Szewczyk A, Kunz WS (2010) Complex III-dependent superoxide production of brain mitochondria contributes to seizure-related ROS formation. Biochim Biophys Acta (Bioenergetics) 1797: 1163-1170
- Malinska D, Kulawiak B, Wrzosek A, Kunz WS, Szewczyk A (2010) The cytoprotective action of the potassium channel opener BMS-191095 in C2C12 myoblasts is related to the modulation of calcium homeostasis. Cell Physiol Biochem. 26: 235-246
- Wojewoda M, Duszyński J, Szczepanowska J. (2010) Antioxidant defence systems and generation of reactive oxygen species in osteosarcoma cells with defective mitochondria: Effect of selenium. Biochim Biophys Acta. (Bioenergetics) 1797(6-7):890-6
- Boratynska A, Martyniszyn L, Szulc L, Krzyzowska M, Szczepanowska J, Niemialtowski MG. (2010) Contribution of rearranged actin structures to the spread of Ectromelia virus infection in vitro. Acta Virol. 54(1):41-8
- Koziel R, Szczepanowska J, Magalska A, Piwocka K, Duszynski J, Zablocki K. (2010) Ciprofloxacin inhibits proliferation and promotes generation of aneuploidy in Jurkat cells. J Physiol Pharmacol. 61(2):233-9
- Onopiuk M, Wierzbicka K, Brutkowski W, Szczepanowska J, Zabłocki K. (2010) Caspase-dependent inhibition of store-operated Ca2+ entry into apoptosis-committed Jurkat cells. Biochem Biophys Res Commun. 399(2):198-202
Laboratory of Bioenergetics and Biomembranes
Nencki Institute of Experimental Biology PAS
3 Pasteur Street, 02-093 Warsaw, Poland
j.duszynski@nencki.gov.pl
Tel. (+48 22) 5892389